A new semester has arrived for Tsukune and the gang featuring a handful of girl obsessed female first years and it seems like among these first years emerges another vampire who holds a grudge against her sister Moka. What shall this grudge lead to in the future and shall Tsukune succeed in taming this new problem child into his friend, no one knows what the future holds.

The new season is set to continue to follow the manga, introduce new characters from the manga and characters created strictly for the anime.